Calendario San Francisco 49ers - 2021

Temporada Regular
SEM	FECHA	OPONENTE	Resultado	G-P	L. Pases	L. Corr.	L. Recib.
1	Dom., 12 de Sep.	en Detroit	G41-33	1-0	Garoppolo 314	Mitchell 104	Samuel 189
2	Dom., 19 de Sep.	en Philadelphia	G17-11	2-0	Garoppolo 189	Mitchell 42	Samuel 93
3	Dom., 26 de Sep.	vs. Green Bay	P30-28	2-1	Garoppolo 257	Sermon 31	Kittle 92
4	Dom., 3 de Oct.	vs. Seattle	P28-21	2-2	Garoppolo 165	Sermon 89	Samuel 156
5	Dom., 10 de Oct.	en Arizona	P17-10	2-3	Lance 192	Lance 89	Samuel 58
6	BYE WEEK
7	Dom., 24 de Oct.	vs. Indianapolis	P30-18	2-4	Garoppolo 181	Mitchell 107	Samuel 100
SEM	FECHA	OPONENTE	HORA	TV	tickets
8	Dom., 31 de Oct.	en Chicago	1:00 PM	FOX	1,961 tickets as low as $134
9	Dom., 7 de Nov.	vs. Arizona	4:25 PM	FOX	3,883 tickets as low as $59
10	Lun., 15 de Nov.	vs. Los Angeles	8:15 PM		5,241 tickets as low as $68
11	Dom., 21 de Nov.	en Jacksonville	1:00 PM	FOX	4,332 tickets as low as $39
12	Dom., 28 de Nov.	vs. Minnesota	4:25 PM	FOX	6,882 tickets as low as $60
13	Dom., 5 de Dic.	en Seattle	8:20 PM	NBC	1,177 tickets as low as $136
14	Dom., 12 de Dic.	en Cincinnati	1:00 PM	CBS	4,944 tickets as low as $43
15	Dom., 19 de Dic.	vs. Atlanta	4:05 PM	CBS	6,347 tickets as low as $55
16	Jue., 23 de Dic.	en Tennessee	8:20 PM	NFL NET	2,764 tickets as low as $62
17	Dom., 2 de Ene.	vs. Houston	4:05 PM	CBS	8,814 tickets as low as $41
18	Dom., 9 de Ene.	en Los Angeles	4:25 PM	FOX	4,290 tickets as low as $110
Pretemporada
SEM	FECHA	OPONENTE	Resultado	G-P	L. Pases	L. Corr.	L. Recib.
1	Sáb., 14 de Ago.	vs. Kansas City	P19-16	0-1	Lance 128	Hasty 63	Sherfield 80
2	Dom., 22 de Ago.	en Los Angeles	G15-10	1-1	Lance 102	Gallman 72	Sherfield 50
3	Dom., 29 de Ago.	vs. Las Vegas	G34-10	2-1	Garoppolo 64	Gallman 60	Sherfield 26