Líderes a la ofensiva
| Yds por aire | YDS | |
Matthew Stafford | 1. Matthew Stafford, LAR | 4707 |
| 2. Jared Goff, DET | 4564 | |
| 3. Dak Prescott, DAL | 4552 | |
| 4. Drake Maye, NE | 4394 | |
| 5. Sam Darnold, SEA | 4048 | |
| Lista Completa | ||
| Yardas por Tierra | YDS | |
James Cook III | 1. James Cook III, BUF | 1621 |
| 2. Derrick Henry, BAL | 1595 | |
| 3. Jonathan Taylor, IND | 1585 | |
| 4. Bijan Robinson, ATL | 1478 | |
| 5. De'Von Achane, MIA | 1350 | |
| Lista Completa | ||
| Yardas Recibiendo | YDS | |
Jaxon Smith-Njigba | 1. Jaxon Smith-Njigba, SEA | 1793 |
| 2. Puka Nacua, LAR | 1715 | |
| 3. George Pickens, DAL | 1429 | |
| 4. Ja'Marr Chase, CIN | 1412 | |
| 5. Amon-Ra St. Brown, DET | 1401 | |
| Lista Completa | ||
Líderes a la defensiva
| Tacleadas | Tack | |
Jordyn Brooks | 1. Jordyn Brooks, MIA | 183 |
| 2. Jack Campbell, DET | 176 | |
| 3. Devin White, LV | 174 | |
| 4. Cedric Gray, TEN | 164 | |
| 5. Bobby Wagner, WSH | 162 | |
| Lista Completa | ||
| Capturas de Mariscal | Capt. | |
Myles Garrett | 1. Myles Garrett, CLE | 23.0 |
| 2. Brian Burns, NYG | 16.5 | |
| 3. Danielle Hunter, HOU | 15.0 | |
| 4. Aidan Hutchinson, DET | 14.5 | |
| 5. Nik Bonitto, DEN | 14.0 | |
| Lista Completa | ||
| Intercepciones | INT | |
Kevin Byard III | 1. Kevin Byard III, CHI | 7 |
| 2. Ernest Jones IV, SEA | 5 | |
| 2. Devin Lloyd, JAX | 5 | |
| 2. Nahshon Wright, CHI | 5 | |
| 2. Antonio Johnson, JAX | 5 | |
| Lista Completa | ||
Información provista por Elias Sports Bureau